We have an NIH-funded postdoctoral position available immediately to study BRAF-driven pediatric brain cancers. You will use ex vivo and in vivo somatic chromosomal engineering to model and characterize pediatric brain tumors driven by the BRAF oncogene, with a particular focus on tumors driven by BRAF gene fusions. The goals include defining the molecular mechanismsContinue reading “We are hiring!”
A brief overview of the HEAP method for miRNA-targets identification.
This year we headed upstate for a two days of sport, science, brainstorming, and good food. Gaspare entertained everybody with his unsuspected skills as piano player and singer. The brainstorming session produced many interesting new ideas, with Nathan, Ram, and Jinny securing the top three places (and an Amazon gift card each!). It wasContinue reading “Retreat 2018: celebrating the first 10 years”
We are happy to announce that our former postdoc Joana Vidigal is starting her own lab at NCI. Given her successes as a grad student and as a postdoc it is easy to predict she will be an outstanding group leader. If you are interested in RNA biology and genome editing, her lab is theContinue reading “Vidigal lab: open for business”
Ping Mu, our very first graduate student, after completing a very successful postdoc with Charles Sawyers, has now started his own lab at UTSW where he will continue his ground breaking work on prostate cancer. If you are looking for a postdoctoral position I cannot think of a better environment and a better lab! ToContinue reading “Ping Mu: from student to PI”
Great news today: Alexander Perez was named to the Forbes 30 under 30 list! This is a prestigious and well-deserved recognition for the important work on CRISPR-Cas9 genome editing he did as a joint MD/PhD student between Christina Leslie’s lab and ours. Way to go Alex!!!
We are proud to announce that our latest manuscript: “Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target”, has been just published in Nature Communications. This work was the result of a truly collaborative effort between our lab and the lab ot our neighbors at MSKCC: Robert Benezra and Maurizio Scaltriti.Continue reading “Modeling brain cancer with CRISPR”
Last Friday was Stephanie Cervino’s last day in our lab. Our fearless admin assistant/lab manager/organizer is going back to school. Needless to say, Stephanie will be missed by us all, but we are comforted by the hope that she will not forget us, and by the certainty that she will do great things! Good luck,Continue reading “A goodbye and a welcome”
The Ventura lab, in collaboration with the Leslie lab, is proud to introduce GuideScan, a new open source software and a companion website that we hope will greatly simplify and improve the design of CRISPR libraries. The GuideScan website allows users to design gRNAs for SpCas9 or for Cpf1 for the most common model organisms, whileContinue reading “Introducing GuideScan”
Today is the last (official) day in the lab for Ciro Bonetti (aka Ciruzzo), one of our senior postdocs. Ciro is leaving to begin a new and exciting adventure at Regeneron. To say that Ciro will be missed is a big understatement and while we are happy for him, he leaves a hole that will be very difficult to fill.Continue reading “Ad majora, Ciro!”