Modeling brain cancer with CRISPR

We are proud to announce that our latest manuscript: “Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target”, has been just published in Nature Communications. This work was the result of a truly collaborative effort  between our lab and the lab ot our neighbors at MSKCC: Robert Benezra and Maurizio Scaltriti.Continue reading “Modeling brain cancer with CRISPR”

A goodbye and a welcome

Last Friday was Stephanie Cervino’s last day in our lab. Our fearless admin assistant/lab manager/organizer is going back to school. Needless to say, Stephanie will be missed by us all, but we are comforted by the hope that she will not forget us, and by the certainty that she will do great things! Good luck,Continue reading “A goodbye and a welcome”

Introducing GuideScan

The Ventura lab, in collaboration with the Leslie lab, is proud to introduce GuideScan, a new open source software and a companion website that we hope will greatly simplify and improve the design of CRISPR libraries. The GuideScan website allows users to design gRNAs for SpCas9 or for Cpf1 for the most common model organisms, whileContinue reading “Introducing GuideScan”