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We are hiring!

We have an NIH-funded postdoctoral position available immediately to study BRAF-driven pediatric brain cancers. You will use ex vivo and in vivo somatic chromosomal engineering to model and characterize pediatric brain tumors driven by the BRAF oncogene, with a particular focus on tumors driven by BRAF gene fusions. The goals include defining the molecular mechanismsContinue reading “We are hiring!”

Ping Mu: from student to PI

Ping Mu, our very first graduate student, after completing  a very successful postdoc with Charles Sawyers, has now started his own lab at UTSW where he will continue his ground breaking work on prostate cancer. If you are looking for a postdoctoral position I cannot think of a better environment and a better lab! ToContinue reading “Ping Mu: from student to PI”

Congratulations Alex!

Great news today: Alexander Perez was named to the Forbes 30 under 30 list! This is a prestigious and well-deserved recognition for the important work on CRISPR-Cas9 genome editing he did as a joint MD/PhD student between Christina Leslie’s lab and ours. Way to go Alex!!!

Modeling brain cancer with CRISPR

We are proud to announce that our latest manuscript: “Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target”, has been just published in Nature Communications. This work was the result of a truly collaborative effort  between our lab and the lab ot our neighbors at MSKCC: Robert Benezra and Maurizio Scaltriti.Continue reading “Modeling brain cancer with CRISPR”

A goodbye and a welcome

Last Friday was Stephanie Cervino’s last day in our lab. Our fearless admin assistant/lab manager/organizer is going back to school. Needless to say, Stephanie will be missed by us all, but we are comforted by the hope that she will not forget us, and by the certainty that she will do great things! Good luck,Continue reading “A goodbye and a welcome”

Introducing GuideScan

The Ventura lab, in collaboration with the Leslie lab, is proud to introduce GuideScan, a new open source software and a companion website that we hope will greatly simplify and improve the design of CRISPR libraries. The GuideScan website allows users to design gRNAs for SpCas9 or for Cpf1 for the most common model organisms, whileContinue reading “Introducing GuideScan”

Ad majora, Ciro!

Today is the last (official) day in the lab for Ciro Bonetti (aka Ciruzzo), one of our senior postdocs. Ciro is leaving to begin a new and exciting adventure at Regeneron. To say that Ciro will be missed is a big understatement and while we are happy for him, he leaves a hole that will be very difficult to fill.Continue reading “Ad majora, Ciro!”

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